A framework for assistive communications technology in cross-cultural healthcare

Rural and remote Australian Aboriginal communities suffer seriously adverse life expectancy rates, lifestyle disease complications and hospital treatment needs due to type 2 diabetes. In great part this is due to communications barriers arising from the lack of equitable acculturation within patient-practitioner consultations. This research presents a framework foundation for a computerised patient-practitioner lingua franca. Behavioural and design science ontology development delivers an intercultural patient-practitioner type 2 diabetes assistive communications system, known as P-PAC

Air Disinfection with Germicidal Ultraviolet:For this Pandemic and the Next

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Redshift z ~ 1 Field Galaxies Observed with the Keck Telescope and the HST

We report results based on 35 new spectroscopic redshifts obtained with the Keck Telescope for field galaxies that also have photometry and morphology from survey images taken by the refurbished HST. A sample of 24 redshifts for galaxies fainter than I = 22 has a median redshift of z ~ 0.81. This result is inconsistent with the lower median redshift of z ~ 0.6 predicted by the ``maximal merger models'' of Carlberg (1996), which otherwise fit existing data. The data match an extrapolation of the CFRS, as well as predictions of certain mild luminosity-evolution models. Nearly half of the redshifts lie in two structures at z ~ 0.81 and z ~ 1.0, showing the presence of high density concentrations spanning scales of ~ 1/h Mpc, i.e., the size of groups. We find emission lines or the presence of possible neighbors in 7 of 9 otherwise luminous galaxies with red central regions at redshifts beyond z ~ 0.7. We also note a diversity of morphological types among blue galaxies at z ~ 1, including small compact galaxies, ``chains,'' and ``blue nucleated galaxies.'' These morphologies are found among local, but generally less luminous, galaxies. Distant blue galaxies also include apparently normal late-type spirals. These findings could imply modest bursts of star formation caused by mergers or interactions of small, gas-rich galaxies with each other or with larger, well-formed galaxies. This first glimpse of very faint z ~ 1 field galaxies of diverse colors and morphologies suggests that a mixture of physical processes is at work in the formation and evolution of faint field galaxies.Comment: 20 pages (31 with table and GIF figures). Full text and postscript figures are available at http://www.ucolick.org/~nicole/pubs/pubs.html#gs1 and http://tarkus.pha.jhu.edu/deep/publications.html . Accepted by The Astrophysical Journa

Learning to treat the climate emergency together: social tipping interventions by the health community

Accelerating the decarbonisation of local and national economies is a profound public health imperative. As trusted voices within communities around the world, health professionals and health organisations have enormous potential to influence the social and policy landscape in support of decarbonisation. We assembled a multidisciplinary, gender-balanced group of experts from six continents to develop a framework for maximising the social and policy influence of the health community on decarbonisation at the micro levels, meso levels, and macro levels of society. We identify practical, learning-by-doing approaches and networks to implement this strategic framework. Collectively, the actions of health-care workers can shift practice, finance, and power in ways that can transform the public narrative and influence investment, activate socioeconomic tipping points, and catalyse the rapid decarbonisation needed to protect health and health systems

Progress report no. 3

Statement of responsibility on title-page reads: editors: M.J. Driscoll, D.D. Lanning, I. Kaplan; contributors: S. T. Brewer, G.J. Brown, P. Delaquil, M.J. Driscoll, G.A. Ducat, I.A. Forbes, M. V. Gregory, S.Y. Ho, M.S. Kalra, C.S. Kang, L.T. Kim, D.D. Lanning, J.L. Lazewatsky, T.C. Leung, E.A. Mason, N.R. Ortiz, N.C. Rasmussen, I.C. Rickard, K.D. Roberson, A.T. Supple, A.M. Thompson, and C.P. TzanosIncludes bibliographical referencesProgress report ; June 30, 1972U.S. Atomic Energy Commission contracts: AT(11-1)306

Plasma Dynamics

Contains research objectives and summary of research on twenty-one projects split into three sections, with four sub-sections in the second section and reports on twelve research projects.National Science Foundation (Grant ENG75-06242)U.S. Energy Research and Development Administration (Contract E(11-1)-2766)U.S. Energy Research and Development Agency (Contract E(11-1)-3070)U.S. Energy Research and Development Administration (Contract E(11-1)-3070)Research Laboratory of Electronics, M.I.T. Industrial Fellowshi

Progress report no. 2

Statement of responsibility on title-page reads: Editors: I.A. Forbes, M.J. Driscoll, N.C. Rasmussen, D.D. Lanning and I. Kaplan; Contributors: S.T. Brewer, G.J. Brown, P.DeLaquil, III, M.J. Driscoll, I.A. Forbes, C.W. Forsberg, E.P. Gyftopoulos, P.L. Hendrick, C.S. Kang, I. Kaplan, J.L. Klucar, D.D. Lanning, T.C. Leung, E.A. Mason, N.R. Ortiz, N.A. Passman, N.C. Rasmussen, I.C. Rickard, V.C. Rogers, G.E. Sullivan, A.T. Supple, and C. P. TzanosIncludes bibliographical referencesProgress report; June 30, 1971U.S. Atomic Energy Commission contract AT(11-1)306

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets

Prostate cancer represents a substantial clinical challenge because it is difficult to predict outcome and advanced disease is often fatal. We sequenced the whole genomes of 112 primary and metastatic prostate cancer samples. From joint analysis of these cancers with those from previous studies (930 cancers in total), we found evidence for 22 previously unidentified putative driver genes harboring coding mutations, as well as evidence for NEAT1 and FOXA1 acting as drivers through noncoding mutations. Through the temporal dissection of aberrations, we identified driver mutations specifically associated with steps in the progression of prostate cancer, establishing, for example, loss of CHD1 and BRCA2 as early events in cancer development of ETS fusion-negative cancers. Computational chemogenomic (canSAR) analysis of prostate cancer mutations identified 11 targets of approved drugs, 7 targets of investigational drugs, and 62 targets of compounds that may be active and should be considered candidates for future clinical trials